Affected by persistent chest pain or tightness?


Affected by persistent chest pain or tightness?

If you are living with angina, this clinical research study might be of interest to you.

Purpose of the study

The purpose of this Caladrius Biosciences, Inc. study is to evaluate the effectiveness and safety of an investigational cell therapy in adults with coronary microvascular dysfunction (CMD) and without obstructive coronary artery disease (CAD). In people with this condition, the small blood vessels that feed the heart muscle do not work properly. As a result, people affected by CMD may experience persistent chest pain or discomfort, especially during physical activity, as their heart is unable to receive enough blood and oxygen. Therefore, CMD increases the risk of serious heart-related complications. Participants in this study may receive investigational treatment targeted at repairing small blood vessels (or “microcirculation”) or placebo.

Who may participate in this study?

You may qualify for this research study, if the following applies to you:

  • You are at least 18 years of age.
  • You have coronary microvascular dysfunction without obstructive coronary artery disease.
  • You are experiencing chest pain or other angina symptoms that limit your daily physical activity.

There are other eligibility requirements. A final decision on whether this research study might be suitable for you will be made after you complete the online and phone questionnaire and speak with the study doctor at the research site. The study doctor will explain the benefits and risks of participating in this research study.

Additional Info

If you provide informed consent to participate in this study, you will be screened for eligibility within 60 days before the start of study treatment. If eligible, you will receive a single dose of the investigational study therapy or placebo. Your health and response to the study treatment will be regularly followed for up to 6 months post-treatment. Your involvement in this study will last approximately 8 months in total.

Cost to Participate

If you qualify and choose to join this research study, you will receive all study-related care at no cost. This includes study treatment, but you may be responsible for costs related to standard of care medical therapy (meaning any care that is not study-related).

Your next steps

  • See if study may be suitable for you by completing an online questionnaire
  • Create a free and secure ClinLife account
  • Be contacted by a ClinLife representative to confirm your details
  • Be contacted by a participating study center for further information
About ClinLife

What is ClinLife?

ClinLife is a free and easy-to-use website helping patients worldwide find the most relevant clinical studies suitable to their medical condition. Listing all available studies by disease area or medical condition, it provides an essential link between research sites and people seeking clinical research studies.

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